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Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain

Impaired dopamine activity in the dorsolateral prefrontal cortex (DLPFC) is thought to contribute to cognitive deficits in diseases such as schizophrenia, attention deficit hyperactivity disorder (ADHD) and traumatic brain injury. Catechol-O-methyltransfease (COMT) metabolizes dopamine and is an imp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Pharmacol
Prif Awduron: Su, Yupin, DePasquale, Michael, Liao, Gangling, Buchler, Ingrid, Zhang, Gongliang, Byers, Spencer, Carr, Gregory V., Barrow, James, Wei, Huijun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962326/
https://ncbi.nlm.nih.gov/pubmed/33503461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2021.173909
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