Binding of calcium and magnesium to human cardiac troponin C

Cardiac muscle thin filaments are composed of actin, tropomyosin, and troponin that change conformation in response to Ca(2+) binding, triggering muscle contraction. Human cardiac troponin C (cTnC) is the Ca(2+)-sensing component of the thin filament. It contains structural sites (III/IV) that bind...

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Vydáno v:J Biol Chem
Hlavní autoři: Rayani, Kaveh, Seffernick, Justin, Li, Alison Yueh, Davis, Jonathan P., Spuches, Anne Marie, Van Petegem, Filip, Solaro, R. John, Lindert, Steffen, Tibbits, Glen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961095/
https://ncbi.nlm.nih.gov/pubmed/33548225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100350
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