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Computer-aided drug discovery approach finds calcium sensitizer of cardiac troponin

In the fight against heart failure, therapeutics that have the ability to increase the contractile power of the heart are urgently needed. One possible route of action to improve heart contractile power is increasing the calcium sensitivity of the thin filament. From a pharmaceutical standpoint, cal...

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書目詳細資料
發表在:Chem Biol Drug Des
Main Authors: Lindert, Steffen, Li, Monica X., Sykes, Brian, McCammon, J. Andrew
格式: Artigo
語言:Inglês
出版: 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456024/
https://ncbi.nlm.nih.gov/pubmed/24954187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12381
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