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Computer-aided drug discovery approach finds calcium sensitizer of cardiac troponin

In the fight against heart failure, therapeutics that have the ability to increase the contractile power of the heart are urgently needed. One possible route of action to improve heart contractile power is increasing the calcium sensitivity of the thin filament. From a pharmaceutical standpoint, cal...

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Dades bibliogràfiques
Publicat a:Chem Biol Drug Des
Autors principals: Lindert, Steffen, Li, Monica X., Sykes, Brian, McCammon, J. Andrew
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456024/
https://ncbi.nlm.nih.gov/pubmed/24954187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12381
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