Apelin Rejuvenates Aged Human Mesenchymal Stem Cells by Regulating Autophagy and Improves Cardiac Protection After Infarction

The protective effects of mesenchymal stem cell (MSC)-based therapy for myocardial infarction (MI) are largely hampered as they age. Apelin is an endogenous ligand of its receptor APJ and plays an essential role in regulating multiple biological activities including MSC proliferation and survival. I...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Zhang, Hao, Zhao, Chengling, Jiang, Guojun, Hu, Bei, Zheng, Huifeng, Hong, Yimei, Cui, Zhen, Shi, Linli, Li, Xin, Lin, Fang, Ding, Yue, Wei, Lu, Li, Mimi, Liang, Xiaoting, Zhang, Yuelin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960672/
https://ncbi.nlm.nih.gov/pubmed/33738284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.628463
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