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Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair

The beneficial functions of mesenchymal stem cells (MSCs) decline with age, limiting their therapeutic efficacy for myocardial infarction (MI). Macrophage migration inhibitory factor (MIF) promotes cell proliferation and survival. We investigated whether MIF overexpression could rejuvenate aged MSCs...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhang, Yuelin, Zhu, Wenwu, He, Haiwei, Fan, Baohan, Deng, Rui, Hong, Yimei, Liang, Xiaoting, Zhao, Hongyan, Li, Xin, Zhang, Fengxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949107/
https://ncbi.nlm.nih.gov/pubmed/31881006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102592
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