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Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and differentiation. There is increasing evidence of the therapeutic value of MSCs in various clinical situations, however, these cells gradually lose their regenerative potential with age, with a concomitant increase in cel...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Liu, Jing, Ding, Yue, Liu, Zhongmin, Liang, Xiaoting
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232554/
https://ncbi.nlm.nih.gov/pubmed/32478063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00258
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