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Analysis of RNA-protein networks with RNP-MaP defines functional hubs on RNA

RNA-protein interaction networks govern many biological processes, but are difficult to examine comprehensively. We devised ribonucleoprotein networks analyzed by mutational profiling (RNP-MaP), a live-cell chemical probing strategy that maps cooperative interactions among multiple proteins bound to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Biotechnol
Prif Awduron: Weidmann, Chase A., Mustoe, Anthony M., Jariwala, Parth B., Calabrese, J. Mauro, Weeks, Kevin M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956044/
https://ncbi.nlm.nih.gov/pubmed/33077962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0709-7
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