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Orthogonal bioluminescent probes from disubstituted luciferins

Bioluminescence imaging with luciferase-luciferin pairs is routinely used to monitor cellular functions. Multiple targets can be visualized in tandem using luciferases that process unique substrates, but only a handful of such orthogonal probes are known. Multiplexed studies require additional robus...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Williams, Sierra J., Hwang, Clare S., Prescher, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955686/
https://ncbi.nlm.nih.gov/pubmed/33599497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00894
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