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Building biological flashlights: Orthogonal luciferases and luciferins for in vivo imaging

Bioluminescence is widely used for real-time imaging in living organisms. This technology features a light-emitting reaction between enzymes (luciferases) and small molecule substrates (luciferins). Photons produced from luciferase-luciferin reactions can penetrate through heterogeneous tissue, enab...

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Bibliographic Details
Published in:Acc Chem Res
Main Authors: Williams, Sierra J., Prescher, Jennifer A.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055158/
https://ncbi.nlm.nih.gov/pubmed/31593431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.9b00391
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