Protein context shapes the specificity of SH3 domain-mediated interactions in vivo

Protein–protein interactions (PPIs) between modular binding domains and their target peptide motifs are thought to largely depend on the intrinsic binding specificities of the domains. The large family of SRC Homology 3 (SH3) domains contribute to cellular processes via their ability to support such...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Dionne, Ugo, Bourgault, Émilie, Dubé, Alexandre K., Bradley, David, Chartier, François J. M., Dandage, Rohan, Dibyachintan, Soham, Després, Philippe C., Gish, Gerald D., Pham, N. T. Hang, Létourneau, Myriam, Lambert, Jean-Philippe, Doucet, Nicolas, Bisson, Nicolas, Landry, Christian R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954794/
https://ncbi.nlm.nih.gov/pubmed/33712617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21873-2
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