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Paralog dependency indirectly affects the robustness of human cells

The protective redundancy of paralogous genes partly relies on the fact that they carry their functions independently. However, a significant fraction of paralogous proteins may form functionally dependent pairs, for instance, through heteromerization. As a consequence, one could expect these hetero...

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Dettagli Bibliografici
Pubblicato in:Mol Syst Biol
Autori principali: Dandage, Rohan, Landry, Christian R
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757259/
https://ncbi.nlm.nih.gov/pubmed/31556487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20198871
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