Direct phosphorylation of Src Homology (SH) 3 domains by tyrosine kinase receptors disassembles ligand-induced signalling networks

Phosphotyrosine (pTyr) signalling has evolved into a key cell-to-cell communication system. Activated receptor tyrosine kinases (RTKs) initiate several pTyr-dependent signalling networks by creating the docking sites required for the assembly of protein complexes. However, the mechanisms leading to...

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Publicado no:Mol Cell
Main Authors: Dionne, Ugo, Chartier, François J. M., de los Santos, Yossef López, Lavoie, Noémie, Bernard, David N., Banerjee, Sara L., Otis, François, Jacquet, Kévin, Tremblay, Michel G., Jain, Mani, Bourassa, Sylvie, Gish, Gerald D., Gagné, Jean-Philippe, Poirier, Guy G., Laprise, Patrick, Voyer, Normand, Landry, Christian R., Doucet, Nicolas, Bisson, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014926/
https://ncbi.nlm.nih.gov/pubmed/29910111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.013
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