Direct phosphorylation of Src Homology (SH) 3 domains by tyrosine kinase receptors disassembles ligand-induced signalling networks

Phosphotyrosine (pTyr) signalling has evolved into a key cell-to-cell communication system. Activated receptor tyrosine kinases (RTKs) initiate several pTyr-dependent signalling networks by creating the docking sites required for the assembly of protein complexes. However, the mechanisms leading to...

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Publicado en:Mol Cell
Autores principales: Dionne, Ugo, Chartier, François J. M., de los Santos, Yossef López, Lavoie, Noémie, Bernard, David N., Banerjee, Sara L., Otis, François, Jacquet, Kévin, Tremblay, Michel G., Jain, Mani, Bourassa, Sylvie, Gish, Gerald D., Gagné, Jean-Philippe, Poirier, Guy G., Laprise, Patrick, Voyer, Normand, Landry, Christian R., Doucet, Nicolas, Bisson, Nicolas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014926/
https://ncbi.nlm.nih.gov/pubmed/29910111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.013
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