Structure and selectivity engineering of the M(1) muscarinic receptor toxin complex

Muscarinic toxins (MTs) are natural toxins produced by mamba snakes that primarily bind to muscarinic acetylcholine receptors (MAChRs) and modulate their function. Despite their similar primary and tertiary structures, MTs show distinct binding selectivity toward different MAChRs. The molecular deta...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Science
Autori principali: Maeda, Shoji, Xu, Jun, Kadji, Francois Marie N., Clark, Mary J., Zhao, Jiawei, Tsutsumi, Naotaka, Aoki, Junken, Sunahara, Roger K., Inoue, Asuka, Garcia, K Christopher, Kobilka, Brian K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954660/
https://ncbi.nlm.nih.gov/pubmed/32646996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax2517
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi