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Crystal structure of human endothelin ET(B) receptor in complex with peptide inverse agonist IRL2500
Endothelin receptors (ET(A) and ET(B)) are G-protein-coupled receptors activated by endothelin-1 and are involved in blood pressure regulation. IRL2500 is a peptide-mimetic of the C-terminal tripeptide of endothelin-1, and has been characterized as a potent ET(B)-selective antagonist, which has prev...
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| 出版年: | Commun Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588608/ https://ncbi.nlm.nih.gov/pubmed/31263780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0482-7 |
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