Crystal structures of human ET(B) receptor provide mechanistic insight into receptor activation and partial activation

Endothelin receptors (ET(A) and ET(B)) are class A GPCRs activated by vasoactive peptide endothelins, and are involved in blood pressure regulation. ET(B)-selective signalling induces vasorelaxation, and thus selective ET(B) agonists are expected to be utilized for improved anti-tumour drug delivery...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Shihoya, Wataru, Izume, Tamaki, Inoue, Asuka, Yamashita, Keitaro, Kadji, Francois Marie Ngako, Hirata, Kunio, Aoki, Junken, Nishizawa, Tomohiro, Nureki, Osamu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226434/
https://ncbi.nlm.nih.gov/pubmed/30413709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07094-0
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items