Caricamento...
Cryo-EM reveals mechanistic insights into lipid-facilitated polyamine export by human ATP13A2
The cytoplasmic polyamine maintains cellular homeostasis by chelating toxic metal cations, regulating transcriptional activity, and protecting DNA. ATP13A2 was identified as a lysosomal polyamine exporter responsible for polyamine release into the cytosol, and its dysfunction is associated with Alzh...
Salvato in:
| Pubblicato in: | Mol Cell |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612442/ https://ncbi.nlm.nih.gov/pubmed/34798056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.11.001 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|