Structure and engineering of the minimal type VI CRISPR-Cas13bt3

Type VI CRISPR-Cas13 effector enzymes catalyze RNA-guided RNA cleavage and have been harnessed for various technologies, such as RNA detection, targeting, and editing. Recent studies identified Cas13bt3 (also known as Cas13X.1) as a miniature Cas13 enzyme, which can be used for knockdown and editing...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Nakagawa, Ryoya, Kannan, Soumya, Altae-Tran, Han, Takeda, Satoru N., Tomita, Atsuhiro, Hirano, Hisato, Kusakizako, Tsukasa, Nishizawa, Tomohiro, Yamashita, Keitaro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613696/
https://ncbi.nlm.nih.gov/pubmed/36027912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2022.08.001
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