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Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation

Genome-wide association studies (GWAS) have uncovered thousands of genetic variants that influence risk for human diseases and traits. Yet understanding the mechanisms by which these genetic variants, mainly noncoding, have an impact on associated diseases and traits remains a significant hurdle. In...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Rao, Shuquan, Yao, Yao, Bauer, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948363/
https://ncbi.nlm.nih.gov/pubmed/33691767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00857-3
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