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Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation
Genome-wide association studies (GWAS) have uncovered thousands of genetic variants that influence risk for human diseases and traits. Yet understanding the mechanisms by which these genetic variants, mainly noncoding, have an impact on associated diseases and traits remains a significant hurdle. In...
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| Published in: | Genome Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948363/ https://ncbi.nlm.nih.gov/pubmed/33691767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00857-3 |
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