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Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation

Genome-wide association studies (GWAS) have uncovered thousands of genetic variants that influence risk for human diseases and traits. Yet understanding the mechanisms by which these genetic variants, mainly noncoding, have an impact on associated diseases and traits remains a significant hurdle. In...

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Bibliografiske detaljer
Udgivet i:Genome Med
Main Authors: Rao, Shuquan, Yao, Yao, Bauer, Daniel E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948363/
https://ncbi.nlm.nih.gov/pubmed/33691767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00857-3
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