Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABA(A) Receptor and In Vivo Zebrafish Studies

BACKGROUND: Recent cryo-electron microscopic imaging studies have shown that in addition to binding to the classical extracellular benzodiazepine binding site of the α(1)β(3)γ(2L) γ-aminobutyric acid type A (GABA(A)) receptor, diazepam also binds to etomidate binding sites located in the transmembra...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Anesthesiology
Autores principales: McGrath, Megan, Hoyt, Helen, Pence, Andrea, Jayakar, Selwyn S., Zhou, Xiaojuan, Forman, Stuart A., Cohen, Jonathan B., Miller, Keith W., Raines, Douglas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944240/
https://ncbi.nlm.nih.gov/pubmed/32541553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003403
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares