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Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABA(A) Receptor and In Vivo Zebrafish Studies
BACKGROUND: Recent cryo-electron microscopic imaging studies have shown that in addition to binding to the classical extracellular benzodiazepine binding site of the α(1)β(3)γ(2L) γ-aminobutyric acid type A (GABA(A)) receptor, diazepam also binds to etomidate binding sites located in the transmembra...
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| Publicado no: | Anesthesiology |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7944240/ https://ncbi.nlm.nih.gov/pubmed/32541553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003403 |
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