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The Effects of a Competitive Antagonist on GABA-evoked Currents in the Presence of Sedative-Hypnotic Agents

BACKGROUND: Many sedative-hypnotic agents are thought to act by positively modulating γ-aminobutyric acid type A (GABA(A)) receptors. However, for many agents, the location(s) of the binding site(s) responsible for such receptor modulation is uncertain. We previously developed a low efficacy ligand...

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Detalhes bibliográficos
Publicado no:Pharmacol Rep
Main Authors: McGrath, Megan, Tolia, Mansi, Raines, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006677/
https://ncbi.nlm.nih.gov/pubmed/32016849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-019-00031-y
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