Are Extrasynaptic GABA(A) Receptors Important Targets for Sedative/Hypnotic Drugs?

High-affinity extrasynaptic GABA(A) receptors are persistently activated by the low ambient GABA levels that are known to be present in extracellular space. The resulting tonic conductance generates a form of shunting inhibition that is capable of altering cellular and network behavior. It has been...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Houston, Catriona M., McGee, Thomas P., MacKenzie, Georgina, Troyano-Cuturi, Kevin, Rodriguez, Pablo Mateos, Kutsarova, Elena, Diamanti, Efthymia, Hosie, Alastair M., Franks, Nicholas P., Brickley, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620914/
https://ncbi.nlm.nih.gov/pubmed/22423109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5406-11.2012
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