Copper Block of Extrasynaptic GABA(A) Receptors in the Mature Cerebellum and Striatum

Inhibition of GABA(A) receptors by Cu(2+) has been appreciated for some time, but differences between synaptic and extrasynaptic GABA(A) receptors have not been explored. We show that Cu(2+) potently blocks steady-state GABA currents mediated by extrasynaptic δ subunit-containing GABA(A) receptors (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McGee, Thomas P., Houston, Catriona M., Brickley, Stephen G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2013
Pynciau:
Brief Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742929/
https://ncbi.nlm.nih.gov/pubmed/23946400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1908-13.2013
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