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Zinc Selectively Blocks Neurosteroid-Sensitive Extrasynaptic δGABA(A) Receptors in the Hippocampus

Zinc (Zn(2+)) is an essential cofactor in mammalian cells and neurons. Zn(2+) is released from synaptic vesicles of certain nerve terminals in the hippocampus during neuronal activity. Zn(2+) has been shown to inhibit synaptic GABA(A) receptors and alter the hippocampal network excitability. However...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Carver, Chase Matthew, Chuang, Shu-Hui, Reddy, Doodipala Samba
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971359/
https://ncbi.nlm.nih.gov/pubmed/27488628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3393-15.2016
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