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NLRX1/FUNDC1/NIPSNAP1‐2 axis regulates mitophagy and alleviates intestinal ischaemia/reperfusion injury

OBJECTIVES: Mitophagy is considered to be a key mechanism in the pathogenesis of intestinal ischaemic reperfusion (IR) injury. NOD‐like receptor X1 (NLRX1) is located in the mitochondria and is highly expressed in the intestine, and is known to modulate ROS production, mitochondrial damage, autophag...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Li, Shaoqin, Zhou, Yi, Gu, Xiaocheng, Zhang, Xiaoping, Jia, Zhongzhi
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941235/
https://ncbi.nlm.nih.gov/pubmed/33432610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12986
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