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NLRX1/FUNDC1/NIPSNAP1‐2 axis regulates mitophagy and alleviates intestinal ischaemia/reperfusion injury

OBJECTIVES: Mitophagy is considered to be a key mechanism in the pathogenesis of intestinal ischaemic reperfusion (IR) injury. NOD‐like receptor X1 (NLRX1) is located in the mitochondria and is highly expressed in the intestine, and is known to modulate ROS production, mitochondrial damage, autophag...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Li, Shaoqin, Zhou, Yi, Gu, Xiaocheng, Zhang, Xiaoping, Jia, Zhongzhi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941235/
https://ncbi.nlm.nih.gov/pubmed/33432610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12986
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