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FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury
Autophagy of mitochondria, termed mitophagy, plays an important role in cerebral ischemia-reperfusion (IR) injury, but the mechanism is not yet clear. Tissue-type plasminogen activator (tPA) is the most important thrombolytic drug in the clinical treatment of ischemic stroke and has neuroprotective...
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| Publicat a: | Redox Biol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7679257/ https://ncbi.nlm.nih.gov/pubmed/33212415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101792 |
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