Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia

Pericytes, important elements of the blood-brain barrier (BBB), play critical roles in maintaining BBB integrity and modulating hemostasis, angiogenesis, inflammation and phagocytic function. We investigated whether pericytes are involved in the recombinant tissue plasminogen activator (rt-PA)-induc...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Yang, Eryan, Cai, Ying, Yao, Xiuhua, Liu, Ji, Wang, Qixue, Jin, Weili, Wu, Qiaoli, Fan, Weijia, Qiu, Lina, Kang, Chunsheng, Wu, Jialing
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914411/
https://ncbi.nlm.nih.gov/pubmed/31740626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102431
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