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NLRX1/FUNDC1/NIPSNAP1‐2 axis regulates mitophagy and alleviates intestinal ischaemia/reperfusion injury

OBJECTIVES: Mitophagy is considered to be a key mechanism in the pathogenesis of intestinal ischaemic reperfusion (IR) injury. NOD‐like receptor X1 (NLRX1) is located in the mitochondria and is highly expressed in the intestine, and is known to modulate ROS production, mitochondrial damage, autophag...

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Dades bibliogràfiques
Publicat a:Cell Prolif
Autors principals: Li, Shaoqin, Zhou, Yi, Gu, Xiaocheng, Zhang, Xiaoping, Jia, Zhongzhi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941235/
https://ncbi.nlm.nih.gov/pubmed/33432610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12986
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