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Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications
Hydroxynorketamines (HNKs) are formed in vivo after (R,S)-ketamine (ketamine) administration. The 12 HNK stereoisomers are distinguished by the position of cyclohexyl ring hydroxylation (at the 4, 5, or 6 position) and their unique stereochemistry at two stereocenters. Although HNKs were initially c...
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| Publicado no: | Pharmacol Rev |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7938660/ https://ncbi.nlm.nih.gov/pubmed/33674359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pharmrev.120.000149 |
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