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Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis
Development of renal fibrosis is a hallmark of renal aging and chronic kidney disease of all etiologies and characterized by extensive renal cell injuries and subsequent myofibroblast transdifferentiations (MTDs), which are significantly influenced by aberrant histone deacetylase (HDAC) activities....
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| Publié dans: | Cell Death Differ |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7937860/ https://ncbi.nlm.nih.gov/pubmed/33024274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00631-9 |
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