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Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis
Development of renal fibrosis is a hallmark of renal aging and chronic kidney disease of all etiologies and characterized by extensive renal cell injuries and subsequent myofibroblast transdifferentiations (MTDs), which are significantly influenced by aberrant histone deacetylase (HDAC) activities....
Gespeichert in:
| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7937860/ https://ncbi.nlm.nih.gov/pubmed/33024274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00631-9 |
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