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Klotho preservation via histone deacetylase inhibition attenuates chronic kidney disease-associated bone injury in mice
Bone loss and increased fracture are the devastating outcomes of chronic kidney disease-mineral and bone disorder (CKD-MBD) resulting from Klotho deficit-related mineral disturbance and hyperparathyroidism. Because Klotho down-regulation after renal injury is presumably affected by aberrant histone...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5384196/ https://ncbi.nlm.nih.gov/pubmed/28387374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46195 |
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