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Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is a common joint disease that can cause gradual disability among the aging population. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key transcription factor that regulates the expression of phase II antioxidant enzymes that provide protection against oxi...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Cai, Dawei, Yin, Shasha, Yang, Jun, Jiang, Qing, Cao, Wangsen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583998/
https://ncbi.nlm.nih.gov/pubmed/26408027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0774-3
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