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Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis

Development of renal fibrosis is a hallmark of renal aging and chronic kidney disease of all etiologies and characterized by extensive renal cell injuries and subsequent myofibroblast transdifferentiations (MTDs), which are significantly influenced by aberrant histone deacetylase (HDAC) activities....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Differ
Päätekijät: Chen, Fang, Gao, Qi, Wei, Ai, Chen, Xingren, Shi, Yujun, Wang, Hongwei, Cao, Wangsen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937860/
https://ncbi.nlm.nih.gov/pubmed/33024274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00631-9
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