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Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis

Development of renal fibrosis is a hallmark of renal aging and chronic kidney disease of all etiologies and characterized by extensive renal cell injuries and subsequent myofibroblast transdifferentiations (MTDs), which are significantly influenced by aberrant histone deacetylase (HDAC) activities....

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Chen, Fang, Gao, Qi, Wei, Ai, Chen, Xingren, Shi, Yujun, Wang, Hongwei, Cao, Wangsen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937860/
https://ncbi.nlm.nih.gov/pubmed/33024274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00631-9
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