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Silencing of Histone Deacetylase 9 Expression in Podocytes Attenuates Kidney Injury in Diabetic Nephropathy

Podocyte dysfunction is important in the onset and development of diabetic nephropathy (DN). Histone deacetylases (HDACs) have been recently proved to play critical roles in the pathogenesis of DN. As one subtype of the class IIa HDACs, HDAC9 is capable to repress/de-repress their target genes in tu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Feng, Zong, Ming, Wen, Xiaofei, Li, Xuezhu, Wang, Jun, Wang, Yi, Jiang, Wei, Li, Xiaojun, Guo, Zhongliang, Qi, Hualin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025656/
https://ncbi.nlm.nih.gov/pubmed/27633396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33676
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