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Silencing of Histone Deacetylase 9 Expression in Podocytes Attenuates Kidney Injury in Diabetic Nephropathy

Podocyte dysfunction is important in the onset and development of diabetic nephropathy (DN). Histone deacetylases (HDACs) have been recently proved to play critical roles in the pathogenesis of DN. As one subtype of the class IIa HDACs, HDAC9 is capable to repress/de-repress their target genes in tu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Feng, Zong, Ming, Wen, Xiaofei, Li, Xuezhu, Wang, Jun, Wang, Yi, Jiang, Wei, Li, Xiaojun, Guo, Zhongliang, Qi, Hualin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025656/
https://ncbi.nlm.nih.gov/pubmed/27633396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33676
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