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T Cell Exhaustion and CAR-T Immunotherapy in Hematological Malignancies

T cell exhaustion has been recognized to play an immunosuppressive role in malignant diseases. Persistent tumor antigen stimulation, the presence of inhibitory immune cells and cytokines in tumor microenvironment (TME), upregulated expression of inhibitory receptors, changes in T cell-related transc...

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Bibliografski detalji
Izdano u:Biomed Res Int
Glavni autori: Tang, Lu, Zhang, Yinqiang, Hu, Yu, Mei, Heng
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936901/
https://ncbi.nlm.nih.gov/pubmed/33728333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6616391
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