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Chimeric Antigen Receptor T Cell Exhaustion during Treatment for Hematological Malignancies

Immunotherapy, especially based on chimeric antigen receptor (CAR) T cells, has achieved prominent success in the treatment of hematological malignancies. However, approximately 30-50% of patients will have disease relapse following remission after receiving CD19-targeting CAR-T cells, with failure...

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Detalles Bibliográficos
Publicado en:Biomed Res Int
Autores principales: Shen, Chunyi, Zhang, Zhen, Zhang, Yi
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603553/
https://ncbi.nlm.nih.gov/pubmed/33150182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8765028
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