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Chimeric antigen receptors for the adoptive T cell therapy of hematologic malignancies

The genetic modification of autologous T cells with chimeric antigen receptors (CARs) represents a breakthrough for gene engineering as a cancer therapy for hematologic malignancies. By targeting the CD19 antigen, we have demonstrated robust and rapid anti-leukemia activity in patients with heavily...

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Dettagli Bibliografici
Pubblicato in:Int J Hematol
Autori principali: Davila, Marco L., Bouhassira, Diana C. G., Park, Jae H., Curran, Kevin J., Smith, Eric L., Pegram, Hollie J., Brentjens, Renier
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684946/
https://ncbi.nlm.nih.gov/pubmed/24311149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-013-1479-5
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