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T Cell Exhaustion and CAR-T Immunotherapy in Hematological Malignancies
T cell exhaustion has been recognized to play an immunosuppressive role in malignant diseases. Persistent tumor antigen stimulation, the presence of inhibitory immune cells and cytokines in tumor microenvironment (TME), upregulated expression of inhibitory receptors, changes in T cell-related transc...
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| Publicat a: | Biomed Res Int |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7936901/ https://ncbi.nlm.nih.gov/pubmed/33728333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6616391 |
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