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The application of CAR-T cell therapy in hematological malignancies: advantages and challenges

Chimeric antigen receptor T cell (CAR-T cell) therapy is a novel adoptive immunotherapy where T lymphocytes are engineered with synthetic receptors known as chimeric antigen receptors (CAR). The CAR-T cell is an effector T cell that recognizes and eliminates specific cancer cells, independent of maj...

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Publicado en:Acta Pharm Sin B
Autores principales: Zhao, Zijun, Chen, Yu, Francisco, Ngiambudulu M., Zhang, Yuanqing, Wu, Minhao
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090008/
https://ncbi.nlm.nih.gov/pubmed/30109179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.03.001
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