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Immune checkpoint blockade and CAR-T cell therapy in hematologic malignancies

Harnessing the power of the immune system to recognize and eliminate cancer cells is a longtime exploration. In the past decade, monoclonal antibody (mAb)-based immune checkpoint blockade (ICB) and chimeric antigen receptor T (CAR-T) cell therapy have proven to be safe and effective in hematologic m...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Wang, Hao, Kaur, Gurbakhash, Sankin, Alexander I., Chen, Fuxiang, Guan, Fangxia, Zang, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558778/
https://ncbi.nlm.nih.gov/pubmed/31186046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0746-1
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