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Immune checkpoint blockade in human cancer therapy: lung cancer and hematologic malignancies
Tumor immune evasion is one of the hallmarks of cancer, and expression of the B7 family of immune checkpoints (PD-L1, PD-L2, B7-H3, B7x and HHLA2) is one mechanism of immune evasion by tumors to suppress T-cell function. Antibodies blocking these interactions of B7–1/B7–2/CTLA-4 and PD-L1/PD-L2/PD-1...
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| Vydáno v: | Immunotherapy |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Future Medicine Ltd
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5619054/ https://ncbi.nlm.nih.gov/pubmed/27349980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2016-0001 |
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