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Epigenetic regulation of p62/SQSTM1 overcomes the radioresistance of head and neck cancer cells via autophagy-dependent senescence induction

Tumors are composed of subpopulations of cancer cells with functionally distinct features. Intratumoral heterogeneity limits the therapeutic effectiveness of cancer drugs. To address this issue, it is important to understand the regulatory mechanisms driving a subclonal variety within a therapy-resi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Death Dis
Κύριοι συγγραφείς: Lee, Myungjin, Nam, Hae Yun, Kang, Hee-Bum, Lee, Won Hyeok, Lee, Geun-Hee, Sung, Gi-Jun, Han, Myung Woul, Cho, Kyung-Ja, Chang, Eun-Ju, Choi, Kyung-Chul, Kim, Seong Who, Kim, Sang Yoon
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935951/
https://ncbi.nlm.nih.gov/pubmed/33674559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03539-5
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