EPHA3 Contributes to Epigenetic Suppression of PTEN in Radioresistant Head and Neck Cancer

EPHA3, a member of the EPH family, is overexpressed in various cancers. We demonstrated previously that EPHA3 is associated with radiation resistance in head and neck cancer via the PTEN/Akt/EMT pathway; the inhibition of EPHA3 significantly enhances the efficacy of radiotherapy in vitro and in vivo...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Kim, Song-Hee, Kang, Byung-Chul, Seong, Daseul, Lee, Won-Hyeok, An, Jae-Hee, Je, Hyoung-Uk, Cha, Hee-Jeong, Chang, Hyo-Won, Kim, Sang-Yoon, Kim, Seong-Who, Han, Myung-Woul
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073943/
https://ncbi.nlm.nih.gov/pubmed/33919657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040599
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