PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies

TARDBP/TDP-43 (TAR DNA binding protein) proteinopathies are a common feature in a variety of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), and Alzheimer disease (AD). However, the molecular mechanisms underlying TARDBP-induced n...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lee, Shinrye, Jeon, Yu-Mi, Cha, Sun Joo, Kim, Seyeon, Kwon, Younghwi, Jo, Myungjin, Jang, You-Na, Lee, Seongsoo, Kim, Jaekwang, Kim, Sang Ryong, Lee, Kea Joo, Lee, Sung Bae, Kim, Kiyoung, Kim, Hyung-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469499/
https://ncbi.nlm.nih.gov/pubmed/31690171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1686729
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